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GABA-B receptor : ウィキペディア英語版
GABAB receptor

GABAB receptors (GABABR) are metabotropic transmembrane receptors for gamma-aminobutyric acid (GABA) that are linked via G-proteins to potassium channels. The changing potassium concentrations hyperpolarize the cell at the end of an action potential.
The reversal potential of the GABAB-mediated IPSP is -100 mV, which is much more hyperpolarized than the GABAA IPSP. GABAB receptors are found in the central as well as in the autonomic division of the peripheral nervous system.
==Functions==
They can stimulate the opening of K+ channels which brings the neuron closer to the equilibrium potential of K+, hyperpolarising the neuron. This prevents voltage-gated sodium channels from opening, action potentials from firing, and VDCCs from opening, and so stops neurotransmitter release. Thus GABAB receptors are considered inhibitory receptors.
GABAB receptors can also reduce the activity of adenylyl cyclase and decrease the cell’s conductance to Ca2+.
GABAB receptors are involved in behavioral actions of ethanol, gamma-Hydroxybutyric acid (GHB), and possibly in pain. Recent research suggests that these receptors may play an important developmental role.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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